#Impact isale series

The median time from first symptom to dyspnea was 5.0 days, to hospital admission was 7.0 days, and to ARDS was 8.0 days. Thirty-six patients (26.1%) were transferred to the intensive care unit (ICU) because of complications, including acute respiratory distress syndrome (22 ), arrhythmia (16 ), and shock (11 ). Most patients received antiviral therapy (oseltamivir, 124 ), and many received antibacterial therapy (moxifloxacin, 89 ceftriaxone, 34 azithromycin, 25 ) and glucocorticoid therapy (62 ). Chest computed tomographic scans showed bilateral patchy shadows or ground glass opacity in the lungs of all patients. Lymphopenia (lymphocyte count, 0.8 × 109/L ) occurred in 97 patients (70.3%), prolonged prothrombin time (13.0 seconds ) in 80 patients (58%), and elevated lactate dehydrogenase (261 U/L ) in 55 patients (39.9%). Common symptoms included fever (136 ), fatigue (96 ), and dry cough (82 ). Hospital-associated transmission was suspected as the presumed mechanism of infection for affected health professionals (40 ) and hospitalized patients (17 ). Results Of 138 hospitalized patients with NCIP, the median age was 56 years (interquartile range, 42-68 range, 22-92 years) and 75 (54.3%) were men. Presumed hospital-related transmission was suspected if a cluster of health professionals or hospitalized patients in the same wards became infected and a possible source of infection could be tracked. Outcomes of critically ill patients and noncritically ill patients were compared. Main Outcomes and Measures Epidemiological, demographic, clinical, laboratory, radiological, and treatment data were collected and analyzed.

#Impact isale series

Design, Setting, and Participants Retrospective, single-center case series of the 138 consecutive hospitalized patients with confirmed NCIP at Zhongnan Hospital of Wuhan University in Wuhan, China, from January 1 to Janufinal date of follow-up was February 3, 2020. Objective To describe the epidemiological and clinical characteristics of NCIP. The number of cases has increased rapidly but information on the clinical characteristics of affected patients is limited. Conversely, in our cohort of patients with acquired NMD, corticosteroids or other immunosuppressants did not appear to be risk factors for more severe COVID-19.Ībstract: Importance In December 2019, novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, China. Diabetes, hypertension and a severe degree of NMD were identified as risk factors of unfavorable outcome following COVID-19. Conclusion During this period, a small percentage of French NMD patients was affected by COVID-19 compared to the general French population and COVID-19 had a limited short-term effect on them. In our cohort, corticosteroids and other immunosuppressants were not significantly associated with higher COVID-19 severity for acquired NMD. Patients with diabetes, hypertension or severe forms of NMD had a higher risk of developing a moderate or severe form of COVID-19. Diabetic patients were at greater risk of dying. COVID-19 caused the death of 9 (11%) NMD patients.

COVID-19 had no effect on NMD for 48 (58%) patients and 48 (58%) patients developed low COVID-19 severity. Results Physicians reported 84 patients, including: 34 with myasthenia gravis, 27 with myopathy and 23 with neuropathy. Clinical data were collected from NMD-COVID-19 patients, between Maand in an anonymous survey carried out by expert physicians from the French Health Care Network Filnemus. The objective of this study was to analyze the prevalence of COVID-19 among NMD patients and the risk factors for its impact and severity during the first wave of the pandemic. TL DR: In this article, the authors analyzed the prevalence of COVID-19 among NMD patients and the risk factors for its impact and severity during the first wave of the pandemic.Ībstract: Background Due to their health condition, patients with neuromuscular diseases (NMD) are at greater risk of developing serious complications with COVID-19.